The origin of grapes dates back thousands of years and in the Caucasus regions between Turkey and Iran, where wild varieties such as Vitis Silvetris grew. Indeed, it seems that the origin of the famous European vine Vitis vinifera is actually Asian. It then spread to Europe where the Greeks began to learn various cultivation techniques to exploit the properties of its fruits. However, it was the Phoenicians who introduced it into the Mediterranean basin and then the Romans who marketed it throughout the West. With human exploration and migration, grapes spread throughout the world: European navigators brought European grape varieties with them to the New World, contributing to the growth of the wine industry in regions such as Latin America, Australia, and California. Today, grapes are cultivated in many climatically different regions, resulting in a wide range of grape varieties and unique wine productions.

The importance of grapes is not only limited to wine production; it is a versatile fruit eaten fresh, dried, or processed into juice and extracts, and its role in cultural traditions is deeply rooted in many societies around the world. In the French vineyards, the viticulture is celebrated with thousand-year-old rituals and food and wine festivals. In Spain, it becomes a table grape or aromatic wine, celebrated in the Fiesta de la Vendimia. Greek culture associates grapes with Dionysus, the god of wine and celebration. Moreover, the grapes, the seeds, the skin, and the juice have long been valued in traditional health remedies for their benefits. Thanks to the high content of antioxidants, vitamins and minerals, and polyphenols, the grape is considered a natural elixir with several health applications ranging from the support of gastrointestinal, cardiovascular, and immune systems to one of the most innovative for cognitive functions.